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Evidence of an outer membrane-located nitroreductase

Recently, different in vitro and in vivo studies reported sepsis-induced changes in the shape of human erythrocytes, which have also been confirmed in animal models and humans [126, 381,382,383,384,385,386,387,388,389]

Longitudinal cohort studies and well-controlled clinical trials are needed to examine sex- and race-specific responses, as well as the impact of genetic variation in antioxidant pathways